Health Advice
- Weight Management
- Quit Smoking
- Acne
- Child Health
- Pain
- Oral Care & Hygiene
- Aneurysm, abdominal aortic
- Tummy ache
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- Periods, absent
- First aid
- Reflux
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- Acupuncture
- Gallbladder, inflammation
- Leukaemia, acute lymphoblastic
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- Addiction
- Addison's disease
- Adenoids and adenoidectomy
- Frozen shoulder
- Agoraphobia
- Air embolism
- Alcohol misuse
- Alcohol poisoning
- Alexander technique
- Rhinitis, allergic
- Indoor allergy
- Mountain sickness
- Alzheimer's disease
- Lazy eye
- Macular degeneration
- Memory loss
- Amniocentesis
- Amputation
- Motor neurone disease
- Steroid misuse
- Iron deficiency anaemia
- Vitamin B12 or folate deficiency anaemia
- Anaesthesia
- Anal fissure
- Brain aneurysm
- Angelman syndrome
- Anger management
- Angina
- Angioedema
- Arteriography
- Stent insertion
- Dog bites
- Fractured ankle
- Ankylosing spondylitis
- Anorexia nervosa
- Smell sense, loss of
- Antacid medicines
- Penicillin
- Anticoagulant medicines
- Antidepressants
- Antifungal medicines
- Antihistamines
- NSAIDs
- Antisocial personality disorder
- Hypochondria
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- Stress
- Appendicitis
- Wrist, broken
- Arterial thrombosis
- Arthritis
- Asbestosis
- Asthma
- Astigmatism
- Eczema
- Atrial fibrillation
- Hearing tests
- Bird flu
- B12 vitamin deficiency
- Skin rashes in babies
- Weaning
- Lumbago (low back pain)
- Septic arthritis
- Halitosis (bad breath)
- Weight loss surgery
- Barium enema
- Bartholin's cyst
- Pressure ulcers
- Bedbugs
- Nocturnal enuresis
- Behçet’s disease
- Facial paralysis
- Tongue pain or soreness
- Prostate enlargement
- Beta-blockers
- Bicarbonate test
- Binge eating
- Biopsy
- Bipolar disorder
- Spider bite
- Eye, black
- Bladder cancer
- Cystitis
- Bladder stones
- Blisters
- Blood donation
- Blood gases test
- Blood groups
- Coughing up blood
- Semen, bloody
- Urine, blood in the
- Vomiting blood
- Septicaemia
- Hypertension
- Low blood pressure
- Blood tests
- Blood transfusion
- Blushing
- Bromhidrosis (body odour)
- Bone cyst
- DXA scan
- Bone marrow donation
- Stem cell transplant
- Borderline personality disorder
- Bottle feeding
- Botulism
- Rectal cancer
- Polyps, bowel
- Leaky gut syndrome
- Orthodontics
- Brain abscess
- Head injury, severe
- Brain tumour, benign (non-cancerous)
- Brain tumour, malignant (cancerous)
- Brain tumours
- Breast abscess
- Breast cancer
- Male breast cancer
- Screening for breast cancer
- Nipple discharge
- Mastitis
- Breast lump
- Breastfeeding
- Shortness of breath
- Osteoporosis
- Fractured collarbone
- Hip fracture
- Leg, broken
- Fractured nose
- Rib injuries
- Toe, broken
- Tooth, broken or knocked out
- Smelly feet (bromodosis)
- Bronchitis
- Teeth grinding
- Thyroid eye disease
- Bulimia
- Burns and scalds
- Heart bypass
- Caesarean section
- Food poisoning
- Cancer
- Thrush
- Thrush, men
- Thrush, oral - adults
- Thrush, oral - babies
- Carbon monoxide poisoning
- Cardiovascular disease
- Cartilage damage
- Nasal congestion
- Rib, cervical
- Smear test
- Sore lips
- Chemotherapy
- Chest infection, adult
- Chest pain
- Herpes zoster virus
- Statins
- Kidney disease, chronic
- Leukaemia, chronic lymphocytic
- Leukaemia, chronic myeloid
- Cirrhosis
- Claustrophobia
- Cluster headaches
- White coated tongue
- Gluten intolerance
- Herpes simplex virus
- Cold
- Colic
- Colostomy
- Coma
- Combined contraceptive pill
- Pneumonia
- CT scan
- Concussion
- Hole in the heart
- Heart failure
- Conjunctivitis
- Constipation
- Contact dermatitis
- Corns and calluses
- Coronary heart disease
- Vegetative state
- Topical corticosteroids
- Steroid medication
- Cosmetic surgery
- Cough
- Counselling
- Leg cramps
- Crohn's disease
- Swallowing pills (problems)
- Undescended testicles
- Lacerations
- Cystic fibrosis
- Psoriatic arthritis
- Dandruff
- Date rape drugs
- Thyroiditis
- Hearing impairment
- Dehydration
- Tooth abscess
- Teething
- Tooth decay
- Fluoride
- False teeth (dentures)
- Depression
- Dyspraxia in children
- Diabetes insipidus
- Diabetes
- Diabetic ketoacidosis
- Diabetic retinopathy
- Dialysis
- Traveller's diarrhoea
- Nutrition
- Rectal examination
- Double vision
- Nummular eczema
- Shoulder dislocation
- Diverticular disease and diverticulitis
- Lightheadedness
- Down's syndrome
- Dry eye syndrome
- Thirst
- Dyslexia
- Periods, painful
- Indigestion
- Swallowing problems
- Dyspraxia (adults)
- Swimmer's ear
- Earache
- Earwax
- Eating disorders
- Ebola virus disease
- Ectopic pregnancy
- Restless legs syndrome
- Endoscopy
- Threadworms
- Tennis elbow
- Epidural
- Epilepsy
- Watering eyes
- Nosebleed
- Impotence
- Tremor (essential)
- Ocular cancer
- Eye injuries
- Red eye
- Falls
- Family planning
- Fever, childhood
- Fibromyalgia
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- Wind
- Seasonal flu
- Nail patella syndrome
- Food allergy
- Foot pain
- Frostbite
- Gallstones
- Stomach removal surgery
- Gastroenteritis
- Gastritis
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- General anaesthetic
- Genetics
- Herpes, genital
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- Gestational diabetes
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- Iron overload disorder
- Haemophilia
- Haemophilus influenzae type b
- Piles (haemorrhoids)
- Ingrown hairs
- Leukaemia, hairy cell
- Hallucinations
- Hamstring injury
- Hand pain
- Tendon repair, hand
- Hand, foot and mouth disease
- Hangover
- Seasonal allergic rhinitis
- Head and neck cancer
- Head injury, minor
- Nits
- Headaches
- Hearing and vision tests for children
- Myocardial infarction
- Heart block
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- Heart transplant
- Heart-lung transplant
- Heat exhaustion and heatstroke
- Sweat rash
- Periods, heavy
- Hepatitis A
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- Herbal medicines
- Hernia, femoral
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- Herpes simplex eye infections
- Hip pain in adults
- Hip replacement
- HIV and AIDS
- Welts
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- Homeopathy
- Hormone replacement therapy (HRT)
- Huntington's disease
- Rabies
- Hyperglycaemia
- Sweating, excessive (hyperhidrosis)
- Joint hypermobility
- Sleepiness in the day (severe and unexplained)
- Thyroid, overactive
- Hypnotherapy
- Testosterone deficiency (hypogonadism)
- Underactive thyroid
- Irritable bowel syndrome
- Painkillers, ibuprofen
- Shoulder tendon, trapped
- Urinary incontinence
- Infertility
- Inflammatory bowel disease
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- Inquest
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- Type 1 diabetes
- Intensive care
- IVF
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- Jaundice
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- knee-pain
- Knee replacement
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- Laxatives
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- Lung transplant
- Lyme disease
- Non-Hodgkin lymphoma
- Lymphoma
- Magnesium test
- MRI scan
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- Male contraceptive pill
- Malnutrition
- Mastectomy
- Rubeola
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- Meningitis
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- Moles
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- Multiple system atrophy
- Mumps
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- Selective mutism
- Short-sightedness
- Nose and sinus cancer
- Polyps, nose
- Nasopharyngeal cancer
- Natural family planning
- Nausea and vomiting in pregnancy
- Peripheral neuropathy
- Night sweats
- Nightmares
- Rhinitis, non-allergic
- Type 2 diabetes
- Winter vomiting disease
- Obesity
- OCD (obsessive compulsive disorder)
- Sleep apnoea
- Occupational therapy
- Swollen ankles
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- Periods, irregular
- Organ donation
- Orthopaedics (orthopaedic surgery)
- Osteoarthritis
- Rickets
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- Pacemaker implantation
- Shoulder pain
- Paracetamol
- Ulcerative colitis
- Pancreas transplant
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- Panic disorder
- Pins and needles
- Paralysis
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- Pelvic pain
- Ulcer, peptic
- Ruptured eardrum
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- Periods
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- Personality disorder
- Whooping cough
- Strep throat
- Phobias
- Physiotherapy
- Pilonidal sinus
- Plastic surgery
- Pleurisy
- Pneumococcal infections
- Poisoning
- Reflux in babies
- Potassium test
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- Prostate disease
- Prostatitis
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- Radiation
- Radiotherapy
- Red blood cell count
- Rheumatic fever
- Rheumatoid arthritis
- Root canal treatment
- Roundworm
- Seasonal affective disorder (SAD)
- Salivary stones
- Salmonella infection
- Scabies
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- Scars
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- Scoliosis
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- Self-harm
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- Sexual health clinics
- STIs
- Shingles
- Social anxiety disorder (social phobia)
- Vomiting in children and babies
- Sinus headache
- Sinusitis
- Skin rashes in children
- Sleep paralysis
- Sleepwalking
- Urine, smelly
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- Spina bifida
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- Squint
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- Stroke
- Stye
- Suicide
- Sunburn
- Swollen glands
- Syphilis
- Tuberculosis (TB)
- Tension-type headaches
- Testicular cancer
- Testicular lumps and swellings
- Thyroid cancer
- Tics
- Tinnitus
- Tongue-tie
- Tonsillitis
- Toothache
- Total iron-binding capacity (TIBC or transferrin) test
- Total protein test
- Tourette's syndrome
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- Traction
- Travel vaccines
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- Urinary tract infection
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- Varicose eczema
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- Vitamins, minerals and supplements
- Vomiting in adults
- Warfarin
- Weight loss (unexpected and unplanned)
- Whiplash
- Wisdom tooth removal
- X-ray
- Yellow fever
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Read moreNHS Choices - Introduction
(03/03/2015)
Antihistamines are a type of medicine often used to treat a number of allergic health conditions.
Although antihistamines can't cure these conditions, they often provide relief from symptoms. For example, antihistamines may be used to treat:
- hay fever
- allergic rhinitis – inflammation of the nose caused by an allergic reaction to substances such as dust mites
- allergic skin conditions, such as eczema or urticaria (hives)
- allergic conjunctivitis – inflammation of the eyes
- allergic reactions caused by insect bites or stings
- mild or moderate allergic reactions caused by food allergies – more severe allergic reactions (anaphylaxis) usually require emergency treatment with adrenaline
Antihistamines also have a number of other uses, such as treating stomach ulcers, insomnia (problems falling asleep) and motion sickness.
Antihistamines are available as
- tablet or capsules (oral antihistamines)
- creams, lotions and gels (topical antihistamines)
- a nasal spray
Many antihistamines are available over the counter at a pharmacy, although some require a prescription.
How antihistamines work
Antihistamines work by altering the way cells are affected by a substance called histamine. Histamine is a chemical the immune system uses to help protect the body's cells against infection.
Usually histamine is a useful substance, but if you're having an allergic reaction it's sometimes necessary to block its effects. Allergic reactions occur when your immune system mistakes a harmless substance, such as pollen, for a threat.
Read more about how antihistamines work.
Types of antihistamine and their effects
Antihistamine medicines are classified in three groups. These are:
- first-generation antihistamines – which cause drowsiness in most people and include diphenhydramine and chlorphenamine
- second- or third-generation antihistamines – which are less likely to cause drowsiness and include loratadine and cetirizine
Second- or third-generation antihistamines are usually recommended. Don't underestimate the levels of drowsiness caused by first-generation antihistamines – their effects can continue into the next day if you take them at night.
An exception to this is sometimes made if the drowsiness caused by first-generation antihistamines can be beneficial, for example in cases where itchy skin may be causing sleep problems.
Read more about the side effects of antihistamines.
Safety
Even though most antihistamines are available without a prescription, you shouldn't assume they're safe for everyone to take.
Antihistamines may have dangerous and unpredictable effects if taken by people with certain conditions or if combined with certain other substances, such as alcohol or certain antidepressants.
It's also important to only take antihistamines as directed. Overdoses are possible and overuse can lead to you becoming reliant on the sedating effects.
Before taking antihistamines, always read the patient information leaflet that comes with the medicine to check the safety information.
Read more about who can use antihistamines and interactions of antihistamines.