Health Advice
- Weight Management
- Quit Smoking
- Acne
- Child Health
- Pain
- Oral Care & Hygiene
- Aneurysm, abdominal aortic
- Tummy ache
- Abscess
- Periods, absent
- First aid
- Reflux
- Blackheads
- Acupuncture
- Gallbladder, inflammation
- Leukaemia, acute lymphoblastic
- Leukaemia, acute myeloid
- Addiction
- Addison's disease
- Adenoids and adenoidectomy
- Frozen shoulder
- Agoraphobia
- Air embolism
- Alcohol misuse
- Alcohol poisoning
- Alexander technique
- Rhinitis, allergic
- Indoor allergy
- Mountain sickness
- Alzheimer's disease
- Lazy eye
- Macular degeneration
- Memory loss
- Amniocentesis
- Amputation
- Motor neurone disease
- Steroid misuse
- Iron deficiency anaemia
- Vitamin B12 or folate deficiency anaemia
- Anaesthesia
- Anal fissure
- Brain aneurysm
- Angelman syndrome
- Anger management
- Angina
- Angioedema
- Arteriography
- Stent insertion
- Dog bites
- Fractured ankle
- Ankylosing spondylitis
- Anorexia nervosa
- Smell sense, loss of
- Antacid medicines
- Penicillin
- Anticoagulant medicines
- Antidepressants
- Antifungal medicines
- Antihistamines
- NSAIDs
- Antisocial personality disorder
- Hypochondria
- Anxiety disorders in children
- Stress
- Appendicitis
- Wrist, broken
- Arterial thrombosis
- Arthritis
- Asbestosis
- Asthma
- Astigmatism
- Eczema
- Atrial fibrillation
- Hearing tests
- Bird flu
- B12 vitamin deficiency
- Skin rashes in babies
- Weaning
- Lumbago (low back pain)
- Septic arthritis
- Halitosis (bad breath)
- Weight loss surgery
- Barium enema
- Bartholin's cyst
- Pressure ulcers
- Bedbugs
- Nocturnal enuresis
- Behçet’s disease
- Facial paralysis
- Tongue pain or soreness
- Prostate enlargement
- Beta-blockers
- Bicarbonate test
- Binge eating
- Biopsy
- Bipolar disorder
- Spider bite
- Eye, black
- Bladder cancer
- Cystitis
- Bladder stones
- Blisters
- Blood donation
- Blood gases test
- Blood groups
- Coughing up blood
- Semen, bloody
- Urine, blood in the
- Vomiting blood
- Septicaemia
- Hypertension
- Low blood pressure
- Blood tests
- Blood transfusion
- Blushing
- Bromhidrosis (body odour)
- Bone cyst
- DXA scan
- Bone marrow donation
- Stem cell transplant
- Borderline personality disorder
- Bottle feeding
- Botulism
- Rectal cancer
- Polyps, bowel
- Leaky gut syndrome
- Orthodontics
- Brain abscess
- Head injury, severe
- Brain tumour, benign (non-cancerous)
- Brain tumour, malignant (cancerous)
- Brain tumours
- Breast abscess
- Breast cancer
- Male breast cancer
- Screening for breast cancer
- Nipple discharge
- Mastitis
- Breast lump
- Breastfeeding
- Shortness of breath
- Osteoporosis
- Fractured collarbone
- Hip fracture
- Leg, broken
- Fractured nose
- Rib injuries
- Toe, broken
- Tooth, broken or knocked out
- Smelly feet (bromodosis)
- Bronchitis
- Teeth grinding
- Thyroid eye disease
- Bulimia
- Burns and scalds
- Heart bypass
- Caesarean section
- Food poisoning
- Cancer
- Thrush
- Thrush, men
- Thrush, oral - adults
- Thrush, oral - babies
- Carbon monoxide poisoning
- Cardiovascular disease
- Cartilage damage
- Nasal congestion
- Rib, cervical
- Smear test
- Sore lips
- Chemotherapy
- Chest infection, adult
- Chest pain
- Herpes zoster virus
- Statins
- Kidney disease, chronic
- Leukaemia, chronic lymphocytic
- Leukaemia, chronic myeloid
- Cirrhosis
- Claustrophobia
- Cluster headaches
- White coated tongue
- Gluten intolerance
- Herpes simplex virus
- Cold
- Colic
- Colostomy
- Coma
- Combined contraceptive pill
- Pneumonia
- CT scan
- Concussion
- Hole in the heart
- Heart failure
- Conjunctivitis
- Constipation
- Contact dermatitis
- Corns and calluses
- Coronary heart disease
- Vegetative state
- Topical corticosteroids
- Steroid medication
- Cosmetic surgery
- Cough
- Counselling
- Leg cramps
- Crohn's disease
- Swallowing pills (problems)
- Undescended testicles
- Lacerations
- Cystic fibrosis
- Psoriatic arthritis
- Dandruff
- Date rape drugs
- Thyroiditis
- Hearing impairment
- Dehydration
- Tooth abscess
- Teething
- Tooth decay
- Fluoride
- False teeth (dentures)
- Depression
- Dyspraxia in children
- Diabetes insipidus
- Diabetes
- Diabetic ketoacidosis
- Diabetic retinopathy
- Dialysis
- Traveller's diarrhoea
- Nutrition
- Rectal examination
- Double vision
- Nummular eczema
- Shoulder dislocation
- Diverticular disease and diverticulitis
- Lightheadedness
- Down's syndrome
- Dry eye syndrome
- Thirst
- Dyslexia
- Periods, painful
- Indigestion
- Swallowing problems
- Dyspraxia (adults)
- Swimmer's ear
- Earache
- Earwax
- Eating disorders
- Ebola virus disease
- Ectopic pregnancy
- Restless legs syndrome
- Endoscopy
- Threadworms
- Tennis elbow
- Epidural
- Epilepsy
- Watering eyes
- Nosebleed
- Impotence
- Tremor (essential)
- Ocular cancer
- Eye injuries
- Red eye
- Falls
- Family planning
- Fever, childhood
- Fibromyalgia
- Flat feet
- Wind
- Seasonal flu
- Nail patella syndrome
- Food allergy
- Foot pain
- Frostbite
- Gallstones
- Stomach removal surgery
- Gastroenteritis
- Gastritis
- Gastroparesis
- Gastroscopy
- General anaesthetic
- Genetics
- Herpes, genital
- Warts, genital
- Rubella
- Gestational diabetes
- Gum disease
- Goitre
- Gout
- Recurrent limb pain in children
- Iron overload disorder
- Haemophilia
- Haemophilus influenzae type b
- Piles (haemorrhoids)
- Ingrown hairs
- Leukaemia, hairy cell
- Hallucinations
- Hamstring injury
- Hand pain
- Tendon repair, hand
- Hand, foot and mouth disease
- Hangover
- Seasonal allergic rhinitis
- Head and neck cancer
- Head injury, minor
- Nits
- Headaches
- Hearing and vision tests for children
- Myocardial infarction
- Heart block
- Palpitations
- Heart transplant
- Heart-lung transplant
- Heat exhaustion and heatstroke
- Sweat rash
- Periods, heavy
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis
- Herbal medicines
- Hernia, femoral
- Hiatus hernia
- Hernia, inguinal
- Hernia, umbilical
- Hernia
- Herpes simplex eye infections
- Hip pain in adults
- Hip replacement
- HIV and AIDS
- Welts
- Lymphoma, Hodgkin
- Homeopathy
- Hormone replacement therapy (HRT)
- Huntington's disease
- Rabies
- Hyperglycaemia
- Sweating, excessive (hyperhidrosis)
- Joint hypermobility
- Sleepiness in the day (severe and unexplained)
- Thyroid, overactive
- Hypnotherapy
- Testosterone deficiency (hypogonadism)
- Underactive thyroid
- Irritable bowel syndrome
- Painkillers, ibuprofen
- Shoulder tendon, trapped
- Urinary incontinence
- Infertility
- Inflammatory bowel disease
- Ingrown toenail
- Inquest
- Insomnia
- Type 1 diabetes
- Intensive care
- IVF
- Jaundice in newborns
- Jaundice
- Stings, sea creatures
- Jet lag
- Joint pain
- Kidney stones
- knee-pain
- Knee replacement
- Knee surgery, anterior cruciate ligament
- Milk intolerance
- Laryngeal (larynx) cancer
- Laryngitis
- Laxatives
- Legionnaires' disease
- Weil's disease
- Liver cancer
- Liver disease
- Liver transplant
- Local anaesthetic
- Twisted neck
- Tetanus
- Loss of libido
- Sperm count, low
- Lumbar puncture
- Swelling or lump
- Lung cancer
- Lung transplant
- Lyme disease
- Non-Hodgkin lymphoma
- Lymphoma
- Magnesium test
- MRI scan
- Malaria
- Male contraceptive pill
- Malnutrition
- Mastectomy
- Rubeola
- Shin splints
- Skin cancer (melanoma)
- Meningitis
- Menopause
- Metallic taste in mouth
- MRSA infection
- Migraine
- Miscarriage
- Mobile phone safety
- Moles
- Travel sickness
- Oral cancer
- Mouth ulcers
- Multiple sclerosis
- Mucositis
- Multiple system atrophy
- Mumps
- Muscular dystrophy
- Selective mutism
- Short-sightedness
- Nose and sinus cancer
- Polyps, nose
- Nasopharyngeal cancer
- Natural family planning
- Nausea and vomiting in pregnancy
- Peripheral neuropathy
- Night sweats
- Nightmares
- Rhinitis, non-allergic
- Type 2 diabetes
- Winter vomiting disease
- Obesity
- OCD (obsessive compulsive disorder)
- Sleep apnoea
- Occupational therapy
- Swollen ankles
- Oesophageal cancer
- Periods, irregular
- Organ donation
- Orthopaedics (orthopaedic surgery)
- Osteoarthritis
- Rickets
- Osteopathy
- Pacemaker implantation
- Shoulder pain
- Paracetamol
- Ulcerative colitis
- Pancreas transplant
- Pancreatic cancer
- Pancreatitis, acute
- Pancreatitis, chronic
- Panic disorder
- Pins and needles
- Paralysis
- Parkinson's disease
- Pelvic pain
- Ulcer, peptic
- Ruptured eardrum
- Pericarditis
- Periods
- Peripheral arterial disease
- Peritonitis
- Personality disorder
- Whooping cough
- Strep throat
- Phobias
- Physiotherapy
- Pilonidal sinus
- Plastic surgery
- Pleurisy
- Pneumococcal infections
- Poisoning
- Reflux in babies
- Potassium test
- Pre-eclampsia
- Slipped disc
- Urinary PSA test
- Prostate disease
- Prostatitis
- Psoriasis
- Puberty
- Radiation
- Radiotherapy
- Red blood cell count
- Rheumatic fever
- Rheumatoid arthritis
- Root canal treatment
- Roundworm
- Seasonal affective disorder (SAD)
- Salivary stones
- Salmonella infection
- Scabies
- Scarlet fever
- Scars
- Schizophrenia
- Sciatica
- Scoliosis
- Scurvy
- Self-harm
- Septic shock
- Sexual health clinics
- STIs
- Shingles
- Social anxiety disorder (social phobia)
- Vomiting in children and babies
- Sinus headache
- Sinusitis
- Skin rashes in children
- Sleep paralysis
- Sleepwalking
- Urine, smelly
- Snake bites
- Snoring
- Spina bifida
- Spinal muscular atrophy
- Sports injuries
- Sprains
- Squint
- Stuttering
- Stomach cancer
- Streptococcal infections
- Stroke
- Stye
- Suicide
- Sunburn
- Swollen glands
- Syphilis
- Tuberculosis (TB)
- Tension-type headaches
- Testicular cancer
- Testicular lumps and swellings
- Thyroid cancer
- Tics
- Tinnitus
- Tongue-tie
- Tonsillitis
- Toothache
- Total iron-binding capacity (TIBC or transferrin) test
- Total protein test
- Tourette's syndrome
- Toxic shock syndrome
- Traction
- Travel vaccines
- Trigger finger
- Typhoid fever
- Ultrasound scan
- Urinary tract infection, children
- Urinary tract infection
- Vaginitis
- Vaginal cancer
- Vaginal discharge
- Varicose eczema
- Varicose veins
- Warts and verrucas
- Vertigo
- Vitamins, minerals and supplements
- Vomiting in adults
- Warfarin
- Weight loss (unexpected and unplanned)
- Whiplash
- Wisdom tooth removal
- X-ray
- Yellow fever
- Bowel cancer screening
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Read moreNHS Choices - Side effects of antihistamines
(03/03/2015)
Like all medicines, antihistamines can have side effects. Generally, these are more significant with first-generation antihistamines.
For a full list of specific side effects of your medicine, see the information leaflet that comes with your medication.
Most information leaflets can also be found online on the Medicines and Healthcare products Regulatory Agency (MHRA) or electronic Medicines Compendium (eMC) websites.
First-generation antihistamines
Common side effects of first-generation antihistamines include:
- drowsiness
- impaired thinking
- dry mouth
- dizziness
- constipation
- blurred vision
- an inability to fully empty the bladder (urinary retention)
It's important not to underestimate the effects of antihistamine-related drowsiness. Some first-generation antihistamines can impair co-ordination, reaction times and judgement in the same way that alcohol consumption can. Therefore you shouldn't drive or use power tools or heavy machinery after taking a first-generation antihistamine.
Less common side effects of first-generation antihistamines include:
- insomnia (difficulty sleeping)
- nightmares
- hallucinations (seeing or hearing things that aren't real)
- itchy skin
Rare side effects of first-generation antihistamines include:
- rapid heartbeat
- chest tightness
Contact your GP if you experience these rare side effects.
Side effects in children
Children have a greater risk of side effects from first-generation antihistamines, particularly drowsiness and impaired thinking.
Second- or third-generation antihistamines
Second- or third-generation antihistamines are less likely to cause drowsiness. If you find yourself feeling drowsy, don't drive, drink alcohol, or use tools or machines.
Other side effects of second- or third-generation antihistamines include:
- headache
- dry mouth
- dry nose
- feeling sick
These side effects don't usually last long and should pass quickly.
Rarer side effects include:
- rapid heartbeat
- chest tightness
However, second- and third-generation antihistamines have been found to have less risk of heart problems than first-generation antihistamines.
Contact your GP if you experience these rare side effects.
H2 receptor antagonists
Antihistamines used to treat stomach ulcers are known as H2 receptor antagonists. Side effects of this type of antihistamine are uncommon but may include:
Yellow Card Scheme
The Yellow Card Scheme allows you to report suspected side effects from any type of medicine you're taking.
It's run by a medicines safety watchdog called the Medicines and Healthcare products Regulatory Agency (MHRA).
See the Yellow Card Scheme website for more information.